Reproduction Abstracts

Introduction: Primordial germ cells (PGCs) are specified during early mammalian post implantation development. They are precursors of adult animals gametes and are considered stem cells of germline. Most of PGCs studies were performed in rodents or human with limited studies in other mammals such as canine. We have recently demonstrated a model to derive embryonic germ cells (EGC) in canine species.Materials and methods: We isolated canine embryos betwee...

Introduction: Spermatogonial stem cells (SSCs) characterized by ability to self-renew and proliferated, differentiated, and transmitted genetic information. In canine the first attempt (1999) of xenotransplantation into mice did not successfully produce spermatozoa. However, there are evidence that xenogeneic transplant of testis cells can engraft in host testis, and generate donor derived sperm; it suggests the SSCs transplantation may offer a similarity to transgenesis in th...